Liquid human milk fortifier significantly improves docosahexaenoic and arachidonic acid status in preterm infants

被引：16
作者：
Berseth, C. L. [1 ]
Harris, C. L. [1 ]
Wampler, J. L. [1 ]
Hoffman, D. R. [2 ]
Diersen-Schade, D. A. [3 ]
机构：
[1] Mead Johnson Nutr, Clin Res, Dept Med Affairs, Evansville, IN 47721 USA
[2] Retina Fdn SW, Dallas, TX 75231 USA
[3] Cornell Univ, Div Nutr Sci, Coll Human Ecol, Ithaca, NY 14853 USA
来源：
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS | 2014年 / 91卷 / 03期
关键词：
Human milk fortifier; Preterm infants; Breast feeding; POLYUNSATURATED FATTY-ACIDS; ALPHA-LINOLENIC ACID; TERM INFANTS; PREMATURE-INFANTS; BREAST-MILK; GROWTH; FORMULA; TRIAL; DIET; DHA;
D O I：
10.1016/j.plefa.2014.03.002
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We report the fatty acid composition of mother's own human milk from one of the largest US cohorts of lactating mothers of preterm infants. Milk fatty acid data were used as a proxy for intake at enrollment in infants (n=150) who received human milk with a powder human milk fortifier (HMF; Control) or liquid HMF [LHMF; provided additional 12 mg docosahexaenoic acid (DHA), 20 mg arachidonic acid (ARA)/100 mL human milk]. Mothers provided milk samples (n=129) and reported maternal DHA consumption (n=128). Infant blood samples were drawn at study completion (Study Day 28). Human milk and infant PPL fatty acids were analyzed using capillary column gas chromatography. DHA and ARA were within ranges previously published for US term and preterm human milk. Compared to Control HMF (providing no DHA or ARA), human milk fortified with LHMF significantly increased infant PPL DHA and ARA and improved preterm infant DHA and ARA status. (C) 2014 The Authors. Published by Elsevier Ltd.
引用
收藏
页码：97 / 103
页数：7
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