Treatment of severe persistent asthma with IL-6 receptor blockade

被引：53
|
作者：
Esty, Brittany [1 ]
Harb, Hani [1 ]
Bartnikas, Lisa M. [1 ]
Charbonnier, Louis M. [1 ]
Massoud, Amir H. [1 ]
Leon-Astudillo, Carmen [2 ]
Visner, Gary [2 ]
Subramaniam, Meera [2 ]
Phipatanakul, Wanda [1 ]
Chatila, Talal A. [1 ]
机构：
[1] Harvard Med Sch, Boston Childrens Hosp, Dept Pediat, Div Immunol, Boston, MA 02115 USA
[2] Harvard Med Sch, Boston Childrens Hosp, Dept Pediat, Div Resp Dis, Boston, MA 02115 USA
来源：
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE | 2019年 / 7卷 / 05期
基金：
美国国家卫生研究院;
关键词：
REGULATORY T-CELLS; AIRWAY INFLAMMATION; ENDOTYPES;
D O I：
10.1016/j.jaip.2019.02.043
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
[No abstract available]
引用
收藏
页码：1639 / +
页数：8
相关论文
共 50 条
  • [1] Systemic IL-6 and Severe Asthma
    Lipworth, Brian
    Chan, Rory
    Kuo, Chris
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 202 (09) : 1324 - 1325
  • [2] Systemic IL-6 and Severe Asthma Reply
    Peters, Michael C.
    Fahy, John V.
    Denlinger, Loren C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 202 (09) : 1325 - 1326
  • [3] IL-6 and Ykl-40 in severe asthma
    Castro, M. C. E.
    Lockett, G.
    Lau, L.
    Barber, C.
    Elliott, S.
    Brown, T.
    Chauhan, A.
    Holloway, J.
    Howarth, P.
    ALLERGY, 2020, 75 : 404 - 405
  • [4] IL-6 AND IL-6 RECEPTOR
    MURAKAMI, M
    HIRANO, T
    SEIKAGAKU, 1990, 62 (01): : 32 - 35
  • [5] Anti-IL-6 receptor antibody increases blood IL-6 level via the blockade of IL-6 clearance, but not via the induction of IL-6 production
    Uchiyama, Yasushi
    Yoshida, Hiroto
    Koike, Nobuo
    Hayakawa, Naohiko
    Sugita, Atsuko
    Nishimura, Takashi
    Mihara, Masahiko
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2008, 8 (11) : 1595 - 1601
  • [6] Serum level of IL-6 and IL-8 in severe and mild asthma
    Adjami, M.
    Hooshiar, B.
    Rafiee, A.
    Ghafari, J.
    Ajami, A.
    ALLERGY, 2011, 66 : 518 - 518
  • [7] Proof of principle of the efficacy of IL-6 receptor blockade in severe systemic juvenile idiopathic arthritis (SJIA)
    Woo, P
    Wilkinson, N
    Prieur, A
    Southwood, T
    Leone, V
    Livermore, P
    Wythe, H
    Thomson, D
    Kishimoto, T
    ANNALS OF THE RHEUMATIC DISEASES, 2005, 64 : 84 - 84
  • [8] The role of IL-6 and IL-6 blockade in COVID-19
    Potere, Nicola
    Batticciotto, Alberto
    Vecchie, Alessandra
    Porreca, Ettore
    Cappelli, Antonella
    Abbate, Antonio
    Dentali, Francesco
    Bonaventura, Aldo
    EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2021, 17 (06) : 601 - 617
  • [9] Role of IL-6 and soluble IL-6 receptor in treatment of treatment resistant bipolar depression (TRBDD)
    Sitar, Evan
    Sinacore, James
    Fareed, Jawed
    Halaris, Angelos
    BIPOLAR DISORDERS, 2023, 25 : 61 - 62
  • [10] Optimized IL-6 Blockade for the Treatment of Diabetic Macular Edema
    Schmidt, Michael
    Tisdale, Alison
    Lowden, Patricia
    Kovalchin, Joseph
    Furfine, Eric S.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2014, 55 (13)
12345