Resting functional connectivity and mild cognitive impairment in Parkinson's disease. An electroencephalogram study

被引：6

作者：

Carmona Arroyave, Jairo Alexander ^{[1
,2
]}

Tobon Quintero, Carlos Andres ^{[1
,2
]}

Suarez Revelo, Jasmin Jimena ^{[1
,3
]}

Ochoa Gomez, John Fredy ^{[1
,3
]}

Bocanegra Garcia, Yamile ^{[1
,2
]}

Moreno Gomez, Leonardo ^{[5
]}

Pineda Salazar, David Antonio ^{[1
,2
,4
]}

机构：

[1] Univ Antioquia, Med Sch, Neurosci Grp, SIU, Calle 62 52-59, Medellin, Colombia

[2] Univ Antioquia, Med Sch, Neuropsychol & Behav Grp GRUNECO, SIU Area Asistencial, Calle 62 52-59, Medellin, Colombia

[3] Univ Antioquia, Bioengn Program, Bioinstrumentat & Clin Engn Res Grp GIBIC, Calle 70 52-21, Medellin, Colombia

[4] Univ San Buenaventura, Psychol Dept, Neuropsychol & Behav Grp GRUNECO, Carrera 56 C 5-110, Medellin, Colombia

[5] Pablo Tobon Uribe Hosp, Neurol Unit, Calle 78B 69-240, Medellin, Colombia

来源：

FUTURE NEUROLOGY | 2019年 / 14卷 / 02期

关键词：

cognitive impairment; electroencephalography; executive functions; functional connectivity; Parkinson's disease; resting state; EARLY ALZHEIMERS-DISEASE; WHITE-MATTER ALTERATION; FRONTAL SCREENING IFS; QUANTITATIVE EEG; EXECUTIVE FUNCTIONS; DOPAMINE DYSFUNCTION; BRAIN NETWORKS; LEWY BODIES; DEMENTIA; SYNCHRONIZATION;

D O I：

10.2217/fnl-2018-0048

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: Parkinson's disease (PD) is characterized by cognitive deficits. There is not clarity about electroencephalogram (EEG) connectivity related to the cognitive profile of patients. Our objective was to evaluate connectivity over resting EEG in nondemented PD. Methods: PD subjects with and without mild cognitive impairment (MCI) were assessed using coherence from resting EEG for local, intra and interhemispheric connectivity. Results: PD subjects without MCI (PD-nMCI) had lower intra and interhemispheric coherence in alpha2 compared with controls. PD with MCI (PD-MCI) showed higher intra and posterior interhemispheric coherence in alpha2 and beta1, respectively, in comparison to PD-nMCI. PD-MCI presented lower frontal coherence in beta frequencies compared with PD-nMCI. Conclusion: EEG coherence measures indicate distinct cortical activity in PD with and without MCI.

引用

页数：16

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