The Clinical Impact of the Lymph Node Ratio as a Prognostic Factor after Resection of Pancreatic Cancer

被引：1

作者：

Yamamoto, Yusuke ^{[1
]}

Ikoma, Hisashi ^{[1
]}

Morimura, Ryo ^{[1
]}

Konishi, Hirotaka ^{[1
]}

Murayama, Yasutoshi ^{[1
]}

Komatsu, Shuhei ^{[1
]}

Shiozaki, Atsushi ^{[1
]}

Kuriu, Yoshiaki ^{[1
]}

Kubota, Takeshi ^{[1
]}

Nakanishi, Masayoshi ^{[1
]}

Ichikawa, Daisuke ^{[1
]}

Fujiwara, Hitoshi ^{[1
]}

Okamoto, Kazuma ^{[1
]}

Sakakura, Chouhei ^{[1
]}

Ochiai, Toshiya ^{[2
]}

Otsuji, Eigo ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Dept Surg, Div Digest Surg, Kamigyo Ku, Kyoto 6028566, Japan

[2] Kyoto Prefectural Univ Med, Dept Surg, Med Ctr N, Kamigyo Ku, Kyoto 6028566, Japan

来源：

ANTICANCER RESEARCH | 2014年 / 34卷 / 05期

关键词：

Pancreatic cancer; pancreatectomy; lymph node metastasis; lymph node ratio; EXTENDED RETROPERITONEAL LYMPHADENECTOMY; PERIAMPULLARY ADENOCARCINOMA; DISTAL GASTRECTOMY; VEIN RESECTION; HEAD CANCER; PANCREATICODUODENECTOMY; SURVIVAL; EXPERIENCE; CARCINOMA; STANDARD;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: The prognostic value of lymph node (LN) status in patients who underwent resection for pancreatic cancer (PC) was examined in the present study. Patients and Methods: Fifty-six patients who underwent macroscopic curative resection for PC were analyzed. Twelve factors, including the number of LN metastases, LN ratio, and N category according to the Japanese Pancreatic Society classification, were analyzed using univariate and multivariate analysis. Results: The optimal cut-off value was 0.2 for the LN ratio. Positive surgical margins (p=0.022) and LN ratio >= 0.2 (p=0.017) were identified as independent prognostic factors. Among the 33 patients with regional LN metastasis, patients with LN ratio >= 0.2 had significantly worse prognosis than those with LN ratio <0.2 (median survival time 14 vs. 26 months, p=0.048), however, the differences in survival between those with N1 and those with N2 by Japanese Pancreatic Society classification were not statistically significant (p=0.85). Conclusion: The LN ratio might be more useful than other parameters as a predictor for survival after resection of PC.

引用

页码：2389 / 2394

页数：6

共 30 条

[1]

[Anonymous], 2010, Japanese Classification of Gastric Carcinoma

[2]

[Anonymous], 2003, Classification of Pancreatic Carcinoma, V2nd

[3] Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes [J].