Optically active titanium complexes containing linked amido-cyclopentadienyl ligands: Their use as asymmetric hydrogenation catalysts

被引：51

作者：

Okuda, J ^{[1
]}

Verch, S ^{[1
]}

Spaniol, TP ^{[1
]}

Sturmer, R ^{[1
]}

机构：

[1] BASF AG,HAUPTLAB,D-67056 LUDWIGSHAFEN,GERMANY

来源：

CHEMISCHE BERICHTE-RECUEIL | 1996年 / 129卷 / 12期

关键词：

titanium complexes; amido-cyclopentadienyl ligand; optically active complexes; asymmetric hydrogenation catalysts; conformational rigidity;

D O I：

10.1002/cber.19961291205

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Optically active titanium complexes of the formula Ti(eta(5):eta(1)- C(5)R(4)SiMe(2)NCHMePh)Cl-2 (R = H, Me), containing the cyclepentadienyl ligand linked to a chiral 1-phenylethylamido moiety, were synthesized and characterized in both enantiomerically pure forms. A single-crystal X-ray structural analysis of (S)-(-)Ti(eta(5):eta(1)-C(5)H(4)SiMe(2)NCHMePh)Cl-2 shows a conformation in which the phenyl group is turned away from the metal center. NOE measurements suggest that a related structure is retained in solution. Upon activation with n-butyllithium, these complexes show hydrogenation activity toward imines with slight enantioselectivity.

引用

页码：1429 / 1431

页数：3

共 30 条

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