Association of Aging, Arterial Stiffness, and Cardiovascular Disease A Review

被引：39

作者：

Veerasamy, Murugapathy ^{[1
,3
]}

Ford, Gary A. ^{[1
,2
]}

Neely, Dermot ^{[4
]}

Bagnall, Alan ^{[1
,3
]}

MacGowan, Guy ^{[3
]}

Das, Rajiv ^{[3
]}

Kunadian, Vijay ^{[1
,3
]}

机构：

[1] Newcastle Univ, Fac Med Sci, Inst Cellular Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

[2] Newcastle Univ, Fac Med Sci, Inst Ageing & Hlth, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

[3] Newcastle Upon Tyne Hosp NHS Fdn Trust, Freeman Hosp, Ctr Cardiothorac, Newcastle Upon Tyne, Tyne & Wear, England

[4] Newcastle Upon Tyne Hosp NHS Fdn Trust, Dept Biochem, Newcastle Upon Tyne, Tyne & Wear, England

来源：

CARDIOLOGY IN REVIEW | 2014年 / 22卷 / 05期

关键词：

arterial stiffness; vascular stiffness; coronary heart disease; cardiovascular disease; coronary artery disease; PULSE-WAVE VELOCITY; NITRIC-OXIDE SYNTHASE; STAGE RENAL-DISEASE; CONVERTING-ENZYME-INHIBITOR; VASCULAR ENDOTHELIAL-CELLS; ASCENDING AORTIC PRESSURE; TYPE-2; DIABETES-MELLITUS; HYPERTENSIVE PATIENTS; AUGMENTATION INDEX; BRACHIAL-ARTERY;

D O I：

10.1097/CRD.0000000000000009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Coronary heart disease (CHD) is the leading cause of morbidity and mortality in the western world. Primary and secondary prevention strategies have improved tremendously. Conventional risk factors are identified and treated with intensive pharmacotherapy. Despite these measures, the incidence of CHD is on the rise in developed countries. Arterial stiffness has been identified as an independent risk factor for the development of CHD, both in the general population and in those with established CHD. This review examines the association of arterial stiffness with cardiovascular disease.

引用

页码：223 / 232

页数：10

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