Dilated cardiomyopathy: a review

被引:113
|
作者
Luk, A. [2 ]
Ahn, E. [1 ]
Soor, G. S. [1 ]
Butany, J. [1 ,3 ]
机构
[1] Toronto Gen Hosp, Dept Pathol, Univ Hlth Network, Toronto, ON M5G 2C4, Canada
[2] Toronto Gen Hosp, Dept Med, Univ Hlth Network, Toronto, ON M5G 2C4, Canada
[3] Univ Toronto, Fac Med, Dept Lab Med & Pathobiol, Toronto, ON, Canada
关键词
CONGESTIVE-HEART-FAILURE; LAMIN A/C; MUTATIONS; GENE; DYSTROPHIN; DIAGNOSIS; LOCALIZATION; MYOCARDITIS; DISRUPTION; GUIDELINES;
D O I
10.1136/jcp.2008.060731
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Dilated cardiomyopathy (DCM) is a common cardiac diagnosis that may result as a consequence of a variety of pathologies. The differential diagnosis remains quite broad since many pathologies can present as DCM, and as a result the approach to diagnosis may, at times, be quite difficult. This review article discusses genetic and acquired causes of DCM, pathophysiology of myocardial damage, pathology, and diagnostic criteria. An approach to management is also included, in the hope of informing physicians of a clinical entity that afflicts a substantial number of people worldwide.
引用
收藏
页码:219 / 225
页数:7
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