Base-catalyzed H/D exchange of polychlorinated biphenyls

被引：4

作者：

Xiang, Zhihao ^{[1
,2
]}

Huang, Shiqing ^{[2
]}

Zhao, Liang-Liang ^{[2
]}

Zhang, Zengyu ^{[2
]}

Chen, Ke ^{[3
]}

Cao, Wanqiang ^{[1
]}

Zheng, Keyu ^{[1
]}

Yan, Xiaoyu ^{[2
]}

机构：

[1] Hubei Univ, Sch Mat Sci & Engn, Wuhan 430062, Peoples R China

[2] Renmin Univ China, Dept Chem, Key Lab Adv Light Convers Mat & Biophoton, Beijing 100872, Peoples R China

[3] South Cent Univ Nationalities, Key Lab Resources Convers & Pollut Control, Coll Resources & Environm Sci, State Ethn Affairs Commiss, Wuhan 430074, Peoples R China

来源：

TETRAHEDRON LETTERS | 2022年 / 110卷

基金：

中国国家自然科学基金;

关键词：

Hydrogen isotope exchange; Deuterium; PCBs; Density functional calculations; DEUTERIUM; COMPLEXES; DRUG;

D O I：

10.1016/j.tetlet.2022.154200

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Polychlorinated biphenyls are one of the most ubiquitous and harmful environmental pollutants at present. With the rapid development of mass spectrometry-based analysis method, it is necessary to develop synthetic methods for isotopologues of polychlorinated biphenyls. Herein, a novel base-catalyzed H/D exchange reaction of polychlorinated biphenyls with DMSO d(6)/D2O has been disclosed. This protocol provides excellent deuterium incorporation with good ortho-selectivity. (C) 2022 Elsevier Ltd. All rights reserved.

引用

页数：5

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