Mucormycosis - from the pathogens to the disease

被引：112
作者：
Binder, U. [1 ]
Maurer, E. [1 ]
Lass-Floerl, C. [1 ]
机构：
[1] Med Univ Innsbruck, Div Hyg & Med Microbiol, A-6020 Innsbruck, Tirol, Austria
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2014年 / 20卷
关键词：
Angioinvasion; iron overload; ketoacidosis; mucorales; mucormycosis; risk factors; zygomycetes; CUTANEOUS MUCORMYCOSIS; RHIZOPUS-ORYZAE; IN-VITRO; HEMATOLOGIC MALIGNANCY; ASPERGILLUS-FUMIGATUS; SAKSENAEA-VASIFORMIS; PATTERN-RECOGNITION; ANTIFUNGAL THERAPY; IRON; ZYGOMYCOSIS;
D O I：
10.1111/1469-0691.12566
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Mucormycosis is an emerging fungal infection worldwide, with devastating disease symptoms and diverse clinical manifestations. The most important underlying risk factors are immunosuppression, poorly controlled diabetes, iron overload and major trauma. The aetiological agents involved in the disease have been re-classified due to changes in taxonomy and nomenclature, which also led to appropriately naming the disease mucormycosis'. This article shortly explains the new nomenclature, clinical manifestations and risk factors and focuses on putative virulence traits associated with mucormycosis, mainly in the group of diabetic ketoacidotic patients.
引用
收藏
页码：60 / 66
页数：7
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