Aggressive angiomyxoma in females: is radical resection the only option?

被引:142
作者
Chan, IM [1 ]
Hon, E [1 ]
Ngai, SW [1 ]
Ng, TY [1 ]
Wong, LC [1 ]
机构
[1] Univ Hong Kong, Queen Mary Hosp, Dept Obstet & Gynecol, Hong Kong, Hong Kong, Peoples R China
关键词
aggressive angiomyxoma; female; treatment;
D O I
10.1034/j.1600-0412.2000.079003216.x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Background. Aggressive angiomyxoma is a rare mesenchymal tumor, characterized by frequent local recurrences. Our aim is to assess the role of radical resection. Methods. Retrospective case review. The records of five patients with aggressive angiomyxoma during the period from 1984 to 1998 were reviewed and analyzed. A MEDLINE search from 1983 to May 1999 was performed. The clinical presentation, surgical treatment, resection margin involvement and clinical outcomes were analyzed. Results. Together with our five cases, 106 cases have been reported in the world literature. The female-to-male ratio was 6.6:1. The age distribution was wide, with the peak incidence at 31 to 35. The local recurrence rate was high. Seventy-one percent of recurrence occurred within the first 3 years. Patients with clear resection margins have similar chances of remaining disease-free compared with those having tumor-involved resection margins. Then was no correlation between the size of the tumors and the chance of recurrence. Conclusions. Though we aim for complete resection, incomplete or partial resection is acceptable, especially when high operative morbidity is anticipated and preservation of fertility is an issue. Long-term follow-up and careful monitoring with imaging techniques are essential for timely identification of recurrence and prompt resection.
引用
收藏
页码:216 / 220
页数:5
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