Cannabinoid receptor, CB1, expression follows neuronal differentiation in the early chick embryo

被引:53
作者
Begbie, J [1 ]
Doherty, P [1 ]
Graham, A [1 ]
机构
[1] Kings Coll London, MRC, Ctr Dev Neurobiol, Mol Neurobiol Grp, London SE1 1UL, England
关键词
CB1; endocannabinoid; neuronal differentiation;
D O I
10.1111/j.0021-8782.2004.00325.x
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
The role of the CB1 cannabinoid receptor and endocannabinoid signalling has been widely studied in the adult nervous system. However, an emerging body of evidence suggests that the CB1 receptor may also play a role during development. Here we have scrutinized the expression profile of the CB1 receptor from the onset of neurogenesis in the chick embryo. We find that this gene exhibits a dynamic expression pattern that spatially and temporally follows neuronal differentiation in the early embryo.
引用
收藏
页码:213 / 218
页数:6
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