pH-responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel Layers with applications for controlled drug release and MR imaging contrast

被引：6

作者：

Huang, Yi-Fong ^{[1
]}

Chiang, Wen-Hsuan ^{[2
]}

Huang, Wen-Chia ^{[2
]}

Chen, Hsin-Hung ^{[1
]}

Shen, Ming-Yin ^{[2
,3
]}

Lin, Sung-Chyr ^{[1
]}

Chern, Chorng-Shyan ^{[4
]}

Chiu, Hsin-Cheng ^{[2
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem Engn, Hsinchu 300, Taiwan

[2] Natl Tsing Hua Univ, Dept Biomed Engn & Environm Sci, Hsinchu 300, Taiwan

[3] Natl Taiwan Univ, Hosp Hsinchu Branch, Dept Surg, Hsinchu 300, Taiwan

[4] Natl Taiwan Univ Sci & Technol, Dept Chem Engn, Taipei 106, Taiwan

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2014年 / 2卷 / 31期

关键词：

TRANSMEMBRANE CHANNELS; CANCER THERANOSTICS; NANOPARTICLES; VESICLES; POLYMERSOMES; NANOGELS; CARRIERS; MICELLE;

D O I：

10.1039/c4tb00771a

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

A cationic lipid-embedded poly(acrylic acid) (PAAc) gel layer coated on chitosan/superparamagnetic iron oxide nanoparticle (SPION) nanohybrid surfaces effectively modulates drug release and MR imaging contrast by pH-responsive morphological transformation and hierarchical alignment of the lipid assemblies.

引用

页码：4988 / 4992

页数：5

共 4 条

[1] pH-Responsive Chitosan/Alginate Polyelectrolyte Complexes on Electrospun PLGA Nanofibers for Controlled Drug Release
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NANOMATERIALS, 2021, 11 (07)
[2] An anti-inflammatory controlled nano drug release and pH-responsive poly lactic acid appended magnetic nanosphere for drug delivery applications
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Webster, Thomas J.
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MATERIALS TODAY COMMUNICATIONS, 2023, 34
[3] Hierarchical hollow monetite microspheres assembled with mesoporous nanosheets: Synthesis and applications in superior adsorbents for lead ions and pH-responsive release drug carrier
Guo, Haifeng
Hu, Siru
Wang, Zongli
Guo, Xinshuang
Wang, Wenbin
Feng, Jun
Zheng, Hong
MATERIALS LETTERS, 2023, 330
[4] In situ doxorubicin-CaP shell formation on amphiphilic gelatin-iron oxide core as a multifunctional drug delivery system with improved cytocompatibility, pH-responsive drug release and MR imaging
Li, W. -M.
Chen, S. -Y.
Liu, D. -M.
ACTA BIOMATERIALIA, 2013, 9 (02) : 5360 - 5368

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