Sulfasalazine-induced hypersensitivity syndrome in a 15-year-old boy associated with human herpesvirus-6 reactivation

被引：9
作者：
Balci, Didem Didar [1 ]
Peker, Erdal [2 ]
Duran, Nizami [3 ]
Dogramaci, Cigdem Asena [1 ]
机构：
[1] Mustafa Kemal Univ, Fac Med, Dept Dermatol, TR-31100 Antakya, Turkey
[2] Mustafa Kemal Univ, Fac Med, Dept Pediat, TR-31100 Antakya, Turkey
[3] Mustafa Kemal Univ, Fac Med, Dept Microbiol, TR-31100 Antakya, Turkey
来源：
CUTANEOUS AND OCULAR TOXICOLOGY | 2009年 / 28卷 / 01期
关键词：
Sulfasalazine; drug-induced hypersensitivity syndrome; human herpesvirus-6 reactivation; DRESS-SYNDROME; SYSTEMIC SYMPTOMS; HEPATOTOXICITY;
D O I：
10.1080/15569520802696250
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Drug-induced hypersensitivity syndrome (DINS) is characterized by high fever, facial edema, diffuse maculopapular eruption, and multiorgan involvement. Human herpesvirus (HHV)-6 reactivation is an accepted criterion for the diagnosis of DINS and has prognostic importance. We report a 15-year-old boy with juvenile rheumatoid arthritis who developed DINS due to sulfasalazine, associated with reactivation of HHV-6.
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收藏
页码：45 / 47
页数：3
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