Sulfasalazine-induced hypersensitivity syndrome in a 15-year-old boy associated with human herpesvirus-6 reactivation

被引：10

作者：

Balci, Didem Didar ^{[1
]}

Peker, Erdal ^{[2
]}

Duran, Nizami ^{[3
]}

Dogramaci, Cigdem Asena ^{[1
]}

机构：

[1] Mustafa Kemal Univ, Fac Med, Dept Dermatol, TR-31100 Antakya, Turkey

[2] Mustafa Kemal Univ, Fac Med, Dept Pediat, TR-31100 Antakya, Turkey

[3] Mustafa Kemal Univ, Fac Med, Dept Microbiol, TR-31100 Antakya, Turkey

来源：

CUTANEOUS AND OCULAR TOXICOLOGY | 2009年 / 28卷 / 01期

关键词：

Sulfasalazine; drug-induced hypersensitivity syndrome; human herpesvirus-6 reactivation; DRESS-SYNDROME; SYSTEMIC SYMPTOMS; HEPATOTOXICITY;

D O I：

10.1080/15569520802696250

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Drug-induced hypersensitivity syndrome (DINS) is characterized by high fever, facial edema, diffuse maculopapular eruption, and multiorgan involvement. Human herpesvirus (HHV)-6 reactivation is an accepted criterion for the diagnosis of DINS and has prognostic importance. We report a 15-year-old boy with juvenile rheumatoid arthritis who developed DINS due to sulfasalazine, associated with reactivation of HHV-6.

引用

页码：45 / 47

页数：3

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