Endovascular repair of ruptured abdominal aortic aneurysm: A strategy in need of definitive evidence
被引:38
作者:
Hinchliffe, Robert J.
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机构:
St Georges Healthcare NHS Trust, St Georges Vasc Inst, London SW17 0QT, EnglandSt Georges Healthcare NHS Trust, St Georges Vasc Inst, London SW17 0QT, England
Hinchliffe, Robert J.
[1
]
Powell, Janet T.
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Univ London Imperial Coll Sci Technol & Med, Vasc Surg Res Grp, London, EnglandSt Georges Healthcare NHS Trust, St Georges Vasc Inst, London SW17 0QT, England
Powell, Janet T.
[2
]
Cheshire, Nicholas J.
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Imperial Coll Healthcare NHS Trust, St Marys Reg Vasc Unit, London, EnglandSt Georges Healthcare NHS Trust, St Georges Vasc Inst, London SW17 0QT, England
Cheshire, Nicholas J.
[3
]
Thompson, Matthew M.
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St Georges Healthcare NHS Trust, St Georges Vasc Inst, London SW17 0QT, EnglandSt Georges Healthcare NHS Trust, St Georges Vasc Inst, London SW17 0QT, England
Thompson, Matthew M.
[1
]
机构:
[1] St Georges Healthcare NHS Trust, St Georges Vasc Inst, London SW17 0QT, England
[2] Univ London Imperial Coll Sci Technol & Med, Vasc Surg Res Grp, London, England
[3] Imperial Coll Healthcare NHS Trust, St Marys Reg Vasc Unit, London, England
Introduction: Endovascular strategies have been increasingly used to manage patients with ruptured abdominal aortic aneurysm (AAA) in an attempt to improve patient survival. We analyzed the evidence to support such an approach. Methods: We performed a systematic literature review of endovascular aneurysm repair (EVAR) of ruptured AAA from 1994 to 2009. The literature analyzed included systematic reviews and population-based studies of ruptured AAA. Results: Seven systematic reviews were identified, all demonstrating from published data that patients with EVAR of ruptured. AAA had significantly reduced mortality compared with controls. Six recently published population-based studies from the United States demonstrated low mortality rates associated with EVAR; however, only a small proportion of ruptured AAAs were treated by EVAR Systematic reviews and population-based studies both raised concerns about patient selection and publication bias. Two, randomized trials are in progress, and one is due to commence 2009. Conclusions: The outcome of EVAR in a nonselected patient population remains unknown. One or more definitive randomized trials could provide the level I evidence to resolve these issues. (J Vase Surg 2009;49:1077-80.)
机构:
Royal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
Harkin, D. W.
Dillon, M.
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Royal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
Dillon, M.
Blair, P. H.
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Royal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
Blair, P. H.
Ellis, P. K.
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Royal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
Ellis, P. K.
Kee, F.
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机构:
Queens Univ Belfast, Dept Epidemiol & Publ Hlth, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
机构:
Royal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
Harkin, D. W.
Dillon, M.
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机构:
Royal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
Dillon, M.
Blair, P. H.
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机构:
Royal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
Blair, P. H.
Ellis, P. K.
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机构:
Royal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland
Ellis, P. K.
Kee, F.
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机构:
Queens Univ Belfast, Dept Epidemiol & Publ Hlth, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Reg Vasc Surg Unit, Belfast BT12 6BA, Antrim, North Ireland