Acute ethylene glycol intoxication. Part I. Pathophysiology and clinical stages

被引:0
|
作者
Gaynor, AR [1 ]
Dhupa, N [1 ]
机构
[1] Tufts Univ, Sch Vet Med, Dept Clin Sci, North Grafton, MA 01536 USA
来源
COMPENDIUM ON CONTINUING EDUCATION FOR THE PRACTICING VETERINARIAN | 1999年 / 21卷 / 11期
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中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Acute ethylene glycol (EG) intoxication is a life-threatening medical emergency characterized by hyperosmolality, profound high anion gap metabolic acidosis, and oliguric or anuric renal failure. Toxic effects and associated clinical signs of this syndrome are caused by both EG and its metabolites, particularly glycolate; however, there is confusion in the medical (human and veterinary) literature regarding the various metabolites of EG and their putative roles in the pathophysiology of this devastating syndrome.
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页码:1014 / +
页数:8
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