Optimal Power for Microwave Slotted Probes in Ablating Different Hepatocellular Carcinoma Sizes

被引:12
作者
Ashour, Amira S. [1 ]
Asran, Menna [1 ]
Fotiadis, Dimitrios I. [2 ,3 ]
机构
[1] Tanta Univ, Dept Elect & Elect Commun Engn, Fac Engn, Tanta, Egypt
[2] Univ Ioannina, Dept Mat Sci & Engn, Unit Med Technol & Intelligent Informat Syst, GR-45110 Ioannina, Greece
[3] FORTH, Inst Mol Biol & Biotechnol, Dept Biomed Res, GR-45110 Ioannina, Greece
关键词
Hepatocellular carcinoma; Tumor size; Microwave ablation; Ablation power; Ablation time; Finite element modeling; RADIOFREQUENCY; LIVER;
D O I
10.1016/j.compbiomed.2020.104101
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Thermal ablation is currently used to treat tumors, whether benign or malignant. The most common types of thermal ablation procedures are the radiofrequency ablation (RFA) and the microwave ablation (MWA). Both generate heat in the tissues leading to an elevation in the tissue temperature level from 50 60 degrees C causing tissues death. In this work, the finite-element method (FEM) is used to model the human liver with a Hepatocellular Carcinoma to obtain the relationship between the power used in microwave radiation, exposure time, and resultant temperature at three microwave frequencies: 433, 915 MHz, and 2.45 GHz. Different hepatic tumor diameters from 20 to 50 mm and the best position to place the probe in the tumor are studied for complete tumor ablation using the lowest required power. A comparison is carried out for four different slotted probes: single slot (SS), multi slot (MS), single slot with 1T ring (SS1T), and single slot with shifted 1T ring (SSST) using the same conditions. The results indicate that the thermal distribution varies according to the type of the used probe. In addition, a relation is deduced between the power and time to assist the physician while using those probes to ablate different tumor sizes. The results reported a reflection coefficient-19.072 dB using the SSS1T probe, while the SS1T provided-4.5582 dB. It is found that a tumor with a diameter of 24, 28, 36, and 39 mm can be completely ablated using power 20 W for a period of 3, 5, 10 and 15 min, respectively, using the SSS1T probe. However, using the same conditions with the SS1T probe, a tumor with diameter 19, 24, 30, and 33 can be ablated, respectively.
引用
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页数:11
相关论文
共 20 条
[1]   A Novel Microwave Coaxial Slot Antenna for Liver Tumor Ablation [J].
Acikgoz, Hulusi ;
Turer, Ibrahim .
ADVANCED ELECTROMAGNETICS, 2014, 3 (01) :20-25
[2]  
Ashour A.S., 2020, IEEE I ELECT ELECT E
[3]   1000 consecutive ablation sessions in the era of computer assisted image guidance - Lessons learned [J].
Beermann, Marie ;
Lindeberg, Johan ;
Engstrand, Jennie ;
Galmen, Karolina ;
Karlgren, Silja ;
Stillstrom, David ;
Nilsson, Henrik ;
Harbut, Piotr ;
Freedman, Jacob .
EUROPEAN JOURNAL OF RADIOLOGY OPEN, 2019, 6 :1-8
[4]   Microwave tissue ablation: Biophysics, technology, and applications [J].
Brace C.L. .
Critical Reviews in Biomedical Engineering, 2010, 38 (01) :65-78
[5]   Radiofrequency and Microwave Ablation of the Liver, Lung, Kidney, and Bone: What Are the Differences? [J].
Brace, Christopher L. .
CURRENT PROBLEMS IN DIAGNOSTIC RADIOLOGY, 2009, 38 (03) :135-143
[6]  
Chang Isaac A, 2010, Open Biomed Eng J, V4, P3, DOI 10.2174/1874120701004020003
[7]  
Gas Piotr, 2018, 2018 International Interdisciplinary PhD Workshop (IIPhDW), P319, DOI 10.1109/IIPHDW.2018.8388381
[8]   Optimization of multi-slot coaxial antennas for microwave thermotherapy based on the S11-parameter analysis [J].
Gas, Piotr .
BIOCYBERNETICS AND BIOMEDICAL ENGINEERING, 2017, 37 (01) :78-93
[9]   MULTI-FREQUENCY ANALYSIS FOR INTERSTITIAL MICROWAVE HYPERTHERMIA USING MULTI-SLOT COAXIAL ANTENNA [J].
Gas, Piotr .
JOURNAL OF ELECTRICAL ENGINEERING-ELEKTROTECHNICKY CASOPIS, 2015, 66 (01) :26-33
[10]   A multi-slot coaxial microwave antenna for liver tumor ablation [J].
Ge, Mengke ;
Jiang, Hejun ;
Huang, Xiaoyan ;
Zhou, Yufu ;
Zhi, Debo ;
Zhao, Gang ;
Chen, Yuping ;
Wang, Lulu ;
Qiu, Bensheng .
PHYSICS IN MEDICINE AND BIOLOGY, 2018, 63 (17)