Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases

被引：48
作者：
Ko, Yanna [1 ,2 ,3 ]
Butcher, Rhys [1 ,2 ,3 ]
Leong, Rupert W. [1 ,2 ,3 ]
机构：
[1] Concord Hosp, Gastroenterol Serv, Sydney, NSW 2139, Australia
[2] Concord Hosp, Liver Serv, Sydney, NSW 2139, Australia
[3] Univ New S Wales, Sydney, NSW 2139, Australia
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2014年 / 20卷 / 05期
基金：
英国医学研究理事会;
关键词：
Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Epidemiology; Risk factor; Environment; Hygiene hypothesis; ISRAELI KIBBUTZ SETTLEMENTS; KINNERET SUB-DISTRICT; TEL-AVIV-YAFO; ULCERATIVE-COLITIS; CROHNS-DISEASE; JEWISH POPULATION; SOUTHERN ISRAEL; CLINICAL EPIDEMIOLOGY; HYGIENE HYPOTHESIS; CIGARETTE-SMOKING;
D O I：
10.3748/wjg.v20.i5.1238
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Inflammatory bowel diseases (IBD) are idiopathic chronic diseases of the gastrointestinal tract well known to be associated with both genetic and environmental risk factors. Permissive genotypes may manifest into clinical phenotypes under certain environmental influences and these may be best studied from migratory studies. Exploring differences between first and second generation migrants may further highlight the contribution of environmental factors towards the development of IBD. There are few opportunities that have been offered so far. We aim to review the available migration studies on IBD, evaluate the known environmental factors associated with IBD, and explore modern migration patterns to identify new opportunities and candidate migrant groups in IBD migration research. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.
引用
收藏
页码：1238 / 1247
页数：10
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