11α-Ethoxy-β-boswellic Acid and Nizwanone, a New Boswellic Acid Derivative and a New Triterpene, Respectively, from Boswellia sacra

被引：14

作者：

Al-Harrasi, Ahmed ^{[1
]}

Ali, Liaqat ^{[1
]}

Rehman, Najeeb Ur ^{[1
]}

Hussain, Javid ^{[1
]}

Hussain, Hidayat ^{[1
]}

Al-Rawahi, Ahmed ^{[1
]}

Rizvi, Tania Shamim ^{[2
]}

机构：

[1] Univ Nizwa, Dept Biol Sci & Chem, Birkat Al Mauz, Nizwa, Oman

[2] Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan

来源：

CHEMISTRY & BIODIVERSITY | 2013年 / 10卷 / 08期

关键词：

Boswellia sacra; -Boswellic acid; 11-ethoxy-; Ursanes; Nizwanone; Triterpenes; OLEOGUM RESIN; APOPTOSIS; CONSTITUENTS; PLANTS;

D O I：

10.1002/cbdv.201200231

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new boswellic acid derivative, 11-ethoxy--boswellic acid (EBA; 1) and a new ursane-type triterpene, named nizwanone (2), were isolated from Omani frankincense Boswellia sacraFlueck. together with two known compounds papyriogenin B and rigidenol. The structures of 1 and 2 were elucidated by detailed spectroscopic analysis using H-1- and C-13-NMR, H-1,H-1-COSY, HMQC, HMBC, and HR-EI-MS techniques. The relative configurations of 1 and 2 were assigned by comparative analysis of the NMR spectral data with those of known analogs together with NOESY experiments. Structures of known compounds were identified by comparison with the reported data.

引用

页码：1501 / 1506

页数：6

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