Recent advances in the synthesis of 1,1-diarylalkanes by transition-metal catalysis

被引：53

作者：

Belal, Md. ^{[1
]}

Li, Zheqi ^{[1
]}

Lu, Xiuqiang ^{[2
]}

Yin, Guoyin ^{[1
]}

机构：

[1] Wuhan Univ, Inst Adv Studies, Wuhan 430072, Peoples R China

[2] Fujian Normal Univ, Fuqing Branch, Sch Ocean Sci & Biochem Engn, Fuzhou 350300, Peoples R China

来源：

SCIENCE CHINA-CHEMISTRY | 2021年 / 64卷 / 04期

基金：

中国国家自然科学基金;

关键词：

transition metal; catalysis; 1,1-diarylalkanes; C-H ACTIVATION; ARYLBORONIC ACIDS; CONJUGATE ADDITION; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC HYDROGENATION; INTERMOLECULAR TRIFLUOROMETHYLARYLATION; QUATERNARY CARBONS; COUPLING REACTIONS; C(SP(3))-H BONDS; CROSS-COUPLINGS;

D O I：

10.1007/s11426-020-9910-2

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1,1-Diaryl moieties are core structures in a wide range of bioactive and pharmaceutical compounds. Transition-metal catalysis is a convenient approach to accessing these invaluable compounds affording high yields and enantioselectivities. This review summarizes 1,1-diarylalkanes synthesis through transition metal catalysis. Particular focus is given to recent developments, such as reductive cross-electrophile couplings, benzylic C-H bond arylation, transformations involving metal migration, asymmetric hydrogenation of 1,1-diarylalkenes and three-component coupling reactions.

引用

收藏

页码：513 / 533

页数：21

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