ASSESSMENT OF REGIONAL BODY COMPOSITION WITH DUAL-ENERGY X-RAY ABSORPTIOMETRY IN DUCHENNE MUSCULAR DYSTROPHY: CORRELATION OF REGIONAL LEAN MASS AND QUANTITATIVE STRENGTH

被引：57

作者：

Skalsky, Andrew J. ^{[1
,2
]}

Han, Jay J. ^{[1
,2
]}

Abresch, Richard T. ^{[1
,2
]}

Shin, Chris S. ^{[1
]}

McDonald, Craig M. ^{[1
,2
]}

机构：

[1] Univ Calif Davis, Dept Phys Med & Rehabil, Sacramento, CA 95817 USA

[2] Univ Calif Davis, NIDRR Rehabil Res & Training Ctr Neuromuscular Di, Sacramento, CA 95817 USA

来源：

MUSCLE & NERVE | 2009年 / 39卷 / 05期

关键词：

BMI; body composition; dual-energy X-ray absorptiometry; fat tissue mass; Duchenne muscular dystrophy; lean tissue mass; muscle strength; SKELETAL-MUSCLE;

D O I：

10.1002/mus.21212

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The purpose of this study was to assess regional body composition and its correlation with regional strength in Duchenne muscular dystrophy (DMD) subjects and able-bodied controls. Regional dual-energy X-ray absorptiometry (DEXA) measurements and isometric strength were obtained for 23 DMD subjects and 23 control subjects. DMD subjects showed a decreased regional lean mass (P < 0.001). The correlation between regional strength and regional lean mass was stronger for controls than for DMD subjects. DMD subjects had decreased regional lean mass, increased regional fat mass, and decreased strength.

引用

页码：647 / 651

页数：5

共 11 条

[1] RELATIONSHIP OF MANUAL MUSCLE TESTING TO OBJECTIVE STRENGTH MEASUREMENTS [J].

AITKENS, S ;

LORD, J ;

BERNAUER, E ;

FOWLER, WM ;

LIEBERMAN, JS ;

BERCK, P .

MUSCLE & NERVE, 1989, 12 (03) :173-177

[2] In vivo determination of intra-myocellular lipids in human muscle by means of localized H-1-MR-spectroscopy [J].

Boesch, C ;

Slotboom, J ;

Hoppeler, H ;

Kreis, R .

MAGNETIC RESONANCE IN MEDICINE, 1997, 37 (04) :484-493

[3] Human skeletal muscle: Sodium MR imaging and quantification-potential applications in exercise and disease [J].

Constantinides, CD ;

Gillen, JS ;

Boada, FE ;

Pomper, MG ;

Bottomley, PA .

RADIOLOGY, 2000, 216 (02) :559-568

[4] DUAL-ENERGY X-RAY ABSORPTIOMETRY IN NEUROMUSCULAR DISEASES [J].

KANDA, F ;

FUJII, Y ;

TAKAHASHI, K ;

FUJITA, T .

MUSCLE & NERVE, 1994, 17 (04) :431-435

[5]

MCDONALD A, 1995, AM J PHYS MED REH S, V74, pS70

[6] Body composition and water compartment measurements in boys with duchenne muscular dystrophy [J].

McDonald, CM ;

Carter, GT ;

Abresch, RT ;

Widman, L ;

Styne, DM ;

Warden, N ;

Kilmer, DD .

AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, 2005, 84 (07) :483-491

[7]

Palmieri GMA, 1996, MUSCLE NERVE, V19, P777

[8] Advances in the application of imaging methods in applied and clinical physiology [J].

Ross, R .

ACTA DIABETOLOGICA, 2003, 40 (Suppl 1) :S45-S50

[9]

Snyder WS., 1974, REPORT TASK GROUP RE

[10]

TAWIL R, 1994, ANN NEUROL, V36, P320

← 1 2 →