Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue

被引：146
作者：
Collingridge, DR
Piepmeier, JM
Rockwell, S
Knisely, JPS
机构：
[1] Yale Univ, Sch Med, Dept Therapeut Radiol, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Dept Neurosurg, New Haven, CT 06520 USA
来源：
RADIOTHERAPY AND ONCOLOGY | 1999年 / 53卷 / 02期
关键词：
tumour oxygenation; brain tumours; glioma; peritumoural tissue;
D O I：
10.1016/S0167-8140(99)00121-8
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This study quantifies the spatial distribution of pO(2) in glioma and in the surrounding brain tissue. Both glioma and peritumoural brain contain regions at oxygen tensions less than 2.5 mmHg. Modalities targeting hypoxia to improve the efficacy of therapy may have an important role in the management of this disease. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：127 / 131
页数：5
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