Blue LED Mediated C-H and N-H Insertion of Indoles into Aryldiazoesters and Iodonium Ylides

被引：0

作者：

Gremaud, Ludovic ^{[1
]}

Sen, Subhabrata ^{[2
]}

机构：

[1] Univ Appl Sci Western Switzerland, Fac Engn & Architecture, Dept Chem, Perolles 80, CH-1700 Fribourg, Switzerland

[2] Shiv Nadar Univ, Sch Nat Sci, Dept Chem, Greater Noida 201314, Uttar Pradesh, India

来源：

CHIMIA | 2022年 / 76卷 / 05期

关键词：

Blue LED; C-H insertion; N-H insertion; Aryldiazoesters; Iodonium ylides; ANTICANCER; INHIBITORS; ANALOGS;

D O I：

10.2533/chimia.2022.483

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein we have discussed projects related to blue LED mediated C-H and N-H insertion reaction in indoles and related heterocycles with aryl diazoesters and iodonium ylides as sources of carbenes. Blue LED effectively facilitates these conversions and was optimized from the option of numerous other LED lights. No metal catalysts were required. The reactions provide formation of differently alkylated indoles, pyrroles and furans. Control experiments and DFT calculation were used to understand the mechanism of reactions. As an application compounds bearing azepino[4, 5-b]indole and spiropiperidino indole building blocks were synthesized from the alkylated products.

引用

页码：483 / 492

页数：10

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