Effects of low molecular weight soybean peptide on mRNA and protein expression levels of differentiation markers in normal human epidermal keratinocytes

被引：1
作者：
Tokudome, Yoshihiro [1 ]
Nakamura, Kyosuke [1 ]
Hashimoto, Fumie [1 ]
机构：
[1] Josai Univ, Fac Pharmaceut Sci, Lab Dermatol Physiol, Sakado, Saitama 35002, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2014年 / 78卷 / 06期
关键词：
low molecular weight soybean peptide; keratinocyte; differentiation; skin; epidermis; ENVELOPE PROTEIN; BARRIER; FILAGGRIN; LORICRIN; PRECURSOR; CELLS;
D O I：
10.1080/09168451.2014.910092
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Low molecular weight soybean peptide (LSP) was applied to normal human epidermal keratinocytes, and the results showed a significant increase in the gene expression levels of involucrin, transglutaminase, and profilaggrin. Filaggrin protein levels were also significantly higher. It is possible that LSP has an epidermal cell differentiation-promoting effect and may be able to regulate metabolism of the epidermis.
引用
收藏
页码：1018 / 1021
页数：4
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