A convenient one-pot synthesis of novel tetraamides via 2-cyclopentylidenemalonic acid based Ugi-four component reaction

被引：10

作者：

Mokhtari, Tayebeh Sattaei ^{[1
]}

Sheikhhosseini, Enayatollah ^{[2
]}

Amrollahi, Mohammad Ali ^{[1
]}

Sheibani, Hassan ^{[3
]}

机构：

[1] Yazd Univ, Coll Sci, Dept Chem, POB 89195-741, Yazd, Iran

[2] Islamic Azad Univ, Dept Chem, Kerman Branch, Kerman, Iran

[3] Shahid Bahonar Univ Kerman, Dept Chem, Kerman 76169, Iran

来源：

JOURNAL OF SAUDI CHEMICAL SOCIETY | 2017年 / 21卷 / 03期

关键词：

Ugi reaction; Multi component reactions (MCRs); 2-Cyclopentylidenemalonic acid; Tetraamides; SOLUTION-PHASE SYNTHESIS; AMIDE BOND FORMATION; MULTICOMPONENT REACTIONS; EFFICIENT SYNTHESIS;

D O I：

10.1016/j.jscs.2015.07.008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A mild and efficient Ugi four component condensation reaction was developed among aromatic aldehydes, aromatic amines, isocyanides and 2-cyclopentylidenemalonic acid to prepare a new series of N-1, N-3 -bis((cyclohexylcarbamoyl)(phenyl) methyl)-2-cyclopentylideneN(1), N-3 -diphenylmalonamide derivatives. These one-pot reactions led to the construction of four amide groups with easy recovery of the desired products. (C) 2015 King Saud University. Production and hosting by Elsevier B.V.

引用

页码：300 / 305

页数：6

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