The role of dendritic cells in neurodegenerative diseases

被引：0
作者：
Iribarren, P [1 ]
Cui, YH [1 ]
Le, YY [1 ]
Wang, JM [1 ]
机构：
[1] NCI, Mol Immunoregulat Lab, Ctr Canc Res, Frederick, MD 21702 USA
来源：
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS | 2002年 / 50卷 / 03期
关键词：
dendritic cells; neurodegenerative diseases; CNS;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs) involved in the induction of adaptive immune responses. The presence of DCs in the central nervous system (CNS) and the active participation of the immune system in a variety of neurodegenerative diseases have been demonstrated. This review will discuss recent findings pertinent to DCs and other antigen-presenting cells in the CNS in health and disease states.
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页码：187 / 196
页数：10
相关论文
共 94 条
  • [1] Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes
    Aloisi, F
    Ria, F
    Adorini, L
    [J]. IMMUNOLOGY TODAY, 2000, 21 (03): : 141 - 147
  • [2] Amat JA, 1996, GLIA, V16, P368, DOI 10.1002/(SICI)1098-1136(199604)16:4<368::AID-GLIA9>3.0.CO
  • [3] 2-W
  • [4] Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
    Aucouturier, P
    Geissmann, F
    Damotte, D
    Saborio, GP
    Meeker, HC
    Kascsak, R
    Kascsak, R
    Carp, RI
    Wisniewski, T
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2001, 108 (05) : 703 - 708
  • [5] Dendritic cells and the control of immunity
    Banchereau, J
    Steinman, RM
    [J]. NATURE, 1998, 392 (6673) : 245 - 252
  • [6] Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
    Bard, F
    Cannon, C
    Barbour, R
    Burke, RL
    Games, D
    Grajeda, H
    Guido, T
    Hu, K
    Huang, JP
    Johnson-Wood, K
    Khan, K
    Kholodenko, D
    Lee, M
    Lieberburg, I
    Motter, R
    Nguyen, M
    Soriano, F
    Vasquez, N
    Weiss, K
    Welch, B
    Seubert, P
    Schenk, D
    Yednock, T
    [J]. NATURE MEDICINE, 2000, 6 (08) : 916 - 919
  • [7] Becher B, 1996, GLIA, V18, P1
  • [8] Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie
    Beekes, M
    McBride, PA
    [J]. NEUROSCIENCE LETTERS, 2000, 278 (03) : 181 - 184
  • [9] Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
    Botto, M
    Dell'Agnola, C
    Bygrave, AE
    Thompson, EM
    Cook, HT
    Petry, F
    Loos, M
    Pandolfi, PP
    Walport, MJ
    [J]. NATURE GENETICS, 1998, 19 (01) : 56 - 59
  • [10] Sequence analysis of rat integrin alpha(E1) and alpha(E2) subunits: tissue expression reveals phenotypic similarities between intraepithelial lymphocytes and dendritic cells in lymph
    Brenan, M
    Rees, DJG
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1997, 27 (11) : 3070 - 3079
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