Regioselective Synthesis of Novel Perfluoroalkylated Fused Pyridines and 3-(Aminomethylene)thiochroman-4-ones from 3-(Perfluoroalkanoyl)thiochromenones and Amines

被引：6

作者：

Kotljarov, Anton ^{[2
,3
]}

Sevenard, Dmitri V. ^{[4
]}

Iaroshenko, Viktor O. ^{[1
,5
]}

Irgashev, Roman A. ^{[6
]}

Volochnyuk, Dmitriy M. ^{[1
]}

Langer, Peter ^{[7
]}

Tolmachev, Andrei A. ^{[1
,5
]}

Sosnovskikh, Vyacheslav Ya. ^{[6
]}

机构：

[1] Enamine Ltd, UA-01103 Kiev, Ukraine

[2] Univ Konstanz, Fachbereich Chem, D-78457 Constance, Germany

[3] Univ Tartu, Inst Organ & Bioorgan Chem, EE-50014 Tartu, Estonia

[4] Hansa Fine Chem GmbH, BITZ, D-28359 Bremen, Germany

[5] Natl Taras Shevchenko Univ, UA-01033 Kiev 33, Ukraine

[6] Ural State Univ, Dept Chem, Ekaterinburg 620083, Russia

[7] Univ Rostock, Inst Chem, D-18059 Rostock, Germany

来源：

SYNTHESIS-STUTTGART | 2010年 / 04期

关键词：

heterocycles; amines; fused-ring systems; thiochromenones; perfluoroalkyl compounds; NICOTINIC-ACID DERIVATIVES; HETERO ANALOGS; 3-(POLYFLUOROACYL)CHROMONES;

D O I：

10.1055/s-0029-1218586

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regioselectivity of reactions of 3-(perfluoroacyl)-4H-thiochromen-4-ones with a range of hetaryl, aryl, and alkyl amines was examined. The reactions provide ready access to poly-fluoroalkylated fused pyridines and thiochromen-4-ones.

引用

页码：671 / 677

页数：7

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