Tumor markers in detection of lung cancer

被引：138
|
作者：
Schneider, Joachim
机构：
[1] Univ Giessen, Inst Arbeits & Sozialmed, D-35385 Giessen, Germany
[2] Univ Giessen, Poliklin Arbeits & Sozialmed, D-35385 Giessen, Germany
来源：
ADVANCES IN CLINICAL CHEMISTRY, VOL 42 | 2006年 / 42卷
关键词：
D O I：
10.1016/S0065-2423(06)42001-1
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
The expression of biomarkers by lung cancers is useful in the diagnosis and clinical management of patients with lung cancer. Biomarkers provide insight into histogenesis, interrelationships, and biological behavior of lung tumors. This chapter presents data on lung cancer detection, involving some of the most studied and interesting lung cancer biomarkers to date-CYFRA 21-1, NSE, ProGRP, SCC, CEA, Tumor M2-PK, as well as markers in clinical application such as CRP, LDH, tumor-suppressor genes and onco-genes, CA125, CgA, NCAM, and TPA. Biomarker profiles in combination with fuzzy logic techniques have also been addressed. Serum markers used alone or in combination with other indices might play an important role in monitoring response to therapy in early detection of tumor reactivation in new treatment strategies as well as in secondary prevention.
引用
收藏
页码：1 / 41
页数：41
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