A highly selective and sensitive turn-on fluorescent probe for the detection of Al3+ and its bioimaging

被引：13
作者：
Wang, Qingming [1 ,2 ]
Yang, Lei [1 ]
Wang, Hua [1 ]
Song, Jialiang [1 ]
Ding, Hui [1 ]
Tang, Xin-Hui [1 ]
Yao, Hongmiao [1 ]
机构：
[1] Yancheng Teachers Univ, Sch Pharm, Jiangsu Prov Key Lab Coastal Wetland Bioresources, Yancheng, Jiangsu, Peoples R China
[2] Nanjing Univ, State Key Lab Coordinat Chem, Nanjing, Jiangsu, Peoples R China
来源：
LUMINESCENCE | 2017年 / 32卷 / 05期
关键词：
Al3+ detection; bioimaging; chemosensor; naphthaldehyde derivative; ALZHEIMERS-DISEASE; SCHIFF-BASE; RAPID DETECTION; ALUMINUM ION; CHEMOSENSOR; SENSOR;
D O I：
10.1002/bio.3251
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A novel fluorescent sensor, 1-((2-hydroxynaphthalen-1-yl)methylene)urea (ocn) has been designed and applied as a highly selective and sensitive fluorescent probe for recognition of Al3+ in Tris-HCl (pH=7.20) solution. The probe ocn exhibits an excellent selectivity to Al3+ over other examined metal ions, anions and amino acids with a prominent fluorescence turn-on' at 438nm. ocn binds to Al3+ with a 2:1 binding stoichiometry and the detection limit was 0.3M. Furthermore, its capability of biological application was evaluated and the results showed that the sensor could be used to detect Al3+ in living cells.
引用
收藏
页码：779 / 785
页数：7
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