Microwave promoted synthesis of some N-(4-methyl-3-tolylthiazol-2(3H)-ylidene) substituted benzamides

被引：4
作者：
Saeed, Aamer [1 ]
机构：
[1] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan
来源：
CHINESE CHEMICAL LETTERS | 2009年 / 20卷 / 09期
关键词：
2-Imino-1,3-thiazoline; Green synthesis; Microwave-accelerated; KINASE INHIBITION ACTIVITIES; CRYSTAL-STRUCTURE; 1-AROYL-3-ARYL-4-SUBSTITUTED IMIDAZOLE-2-THIONES; DERIVATIVES; 2-IMINO-1,3-THIAZOLINES; 2-AMINOTHIAZOLES; THIAZOLINE; EFFICIENT; RECEPTOR; WATER;
D O I：
10.1016/j.cclet.2009.04.016
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
N-(4-Methyl-3-tolylthiazol-2(3H)-yhdene) substituted benzamides (2a-o) were synthesized in good to excellent yields by the base-catalyzed direct cyclization of corresponding 1-tolyl-3-aryl thioureas (1a-o) with 2-bromoacetone through microwave irradiation in a solvent-free medium. Compared to traditional thermal heating, microwave irradiation provides a much more cleaner, efficient and faster method for synthesis of the title compounds. (C) 2009 Aamer Saeed. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：1073 / 1076
页数：4
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