Variations on ligand-receptor complexes

被引:0
|
作者
Wiesmann, C
de Vos, AM
机构
[1] Genentech Inc, Dept Prot Engn, S San Francisco, CA 94080 USA
[2] Sunesis Pharmaceut Inc, Redwood City, CA 94063 USA
来源
NATURE STRUCTURAL BIOLOGY | 2000年 / 7卷 / 06期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The complex between BMP-2, a TGF-beta family member, and its high affinity receptor provides new Insights into the assembly of receptor complexes for members of the cystine-knot growth factor family. A novel proposal for the interaction between Flt3L and its receptor suggests a general scheme for the interaction of closely related receptor tyrosine kinases with structurally diverse ligands, including certain members of the TGF-beta family.
引用
收藏
页码:440 / 442
页数:3
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