DC-virus interplay: a double edged sword

被引：43

作者：

Larsson, M ^{[1
]}

Beignon, AS ^{[1
]}

Bhardwaj, N ^{[1
]}

机构：

[1] NYU, Sch Med, New York, NY 10016 USA

来源：

SEMINARS IN IMMUNOLOGY | 2004年 / 16卷 / 03期

关键词：

myeloid dendritic cells; plasmacytoid dendritic cells; virus; immunity;

D O I：

10.1016/j.smim.2004.02.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Myeloid and plasmacytoid dendritic cells, a family of professional antigen presenting cells, are crucial in generating and maintaining anti-viral immunity. Many viruses have evolved to avoid, subvert, and even counterattack them. In this article, we focus on the tuning of innate and adaptive responses induced by human dendritic cells, and on the inhibition of their functions by viruses of medical significance. A constant "tug of war" goes on between dendritic cells and viruses and a main dendritic cell countermeasure is cross-presentation/priming. (C) 2004 Elsevier Ltd. All rights reserved.

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收藏

页码：147 / 161

页数：15

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