Radical trachelectomy: The first step of fertility preservation in young women with cervical cancer

被引:38
作者
Gizzo, Salvatore [1 ]
Ancona, Emanuele [1 ]
Saccardi, Carlo [1 ]
Patrelli, Tito Silvio [2 ]
Berretta, Roberto [2 ]
Anis, Omar [1 ]
Noventa, Marco [1 ]
Bertocco, Anna [1 ]
Fagherazzi, Simone [1 ]
Longone, Michela [1 ]
Vendemiati, Lucia [1 ]
D'Antona, Donato [1 ]
Nardelli, Giovanni Battista [1 ]
机构
[1] Univ Padua, Dept Womens & Childrens Hlth, Padua, Italy
[2] Univ Parma, Dept Surg Sci, I-43100 Parma, Italy
关键词
radical trachelectomy; cervical cancer; young women; future pregnancy desire; subsequent fertility rat; PELVIC LYMPHADENECTOMY; VAGINAL TRACHELECTOMY; PRESERVING OPTION; DARGENTS OPERATION; SPARING SURGERY; HYSTERECTOMY; CARCINOMA; SERIES; OUTCOMES;
D O I
10.3892/or.2013.2736
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Radical trachelectomy (RT) can be performed vaginally or abdominally (laparotomic, laparoscopic or robotic). The aim of this systematic review was to compare all techniques in terms of surgical complications, disease recurrence and subsequent fertility/pregnancy outcomes. A total of 1293 RTs were analyzed (FIGO-stage: IA1-IIA). The most frequent surgical complications do not differ from the ones of radical hysterectomy. The recurrence risk is approximately 3% (range 0-16.8%). The majority of women conceive spontaneously: 284 pregnancies with 173 live births. The most frequent pregnancy complication was miscarriage and chorioamnionitis. RT appears to be a safe option for eligible women who intend to maintain their future pregnancy desire.
引用
收藏
页码:2545 / 2554
页数:10
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