Comparison of motor, cognitive, and behavioral features in progressive supranuclear palsy and Parkinson's disease

被引：37

作者：

Cordato, NJ ^{[1
]}

Halliday, GA

Caine, D

Morris, JGL

机构：

[1] Westmead Hosp, Dept Geriatr Med, Westmead, NSW 2145, Australia

[2] Univ Sydney, Westmead, NSW 2145, Australia

[3] Prince Wales Med Res Inst, Sydney, NSW, Australia

[4] Univ New S Wales, Sydney, NSW, Australia

[5] Westmead Hosp, Dept Neurol, Westmead, NSW 2145, Australia

来源：

MOVEMENT DISORDERS | 2006年 / 21卷 / 05期

关键词：

PSP; Parkinson's disease; motor features; cognition; behavior;

D O I：

10.1002/mds.20779

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Major clinical features and global measures were systematically evaluated and compared in progressive supranuclear palsy (PSP) and Parkinson's disease (PD). In addition to gaze palsy and early postural instability in PSP, absence of levodopa-induced dyskinesia, frontalis muscle overactivity, primitive reflexes, visuospatial impairment, and substantial frontal behavioral disturbances differentiated almost all patients with this disorder from PD. For PSP, behavioral changes related to severity of general disability, thereby challenging previous models of relationships between behavior, motor, and cognitive disturbance for this disorder. (C) 2005 Movement Disorder Society.

引用

页码：632 / 638

页数：7

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