Molecular mechanisms of translational control

被引：736
|
作者：
Gebauer, F
Hentze, MW
机构：
[1] Ctr Regulacio Genom, Barcelona 08003, Spain
[2] European Mol Biol Lab, D-69117 Heidelberg, Germany
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2004年 / 5卷 / 10期
关键词：
D O I：
10.1038/nrm1488
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Translational control is widely used to regulate gene expression. This mode of regulation is especially relevant in situations where transcription is silent or when local control over protein accumulation is required. Although many examples of translational regulation have been described, only a few are beginning to be mechanistically understood. Instead of providing a comprehensive account of the examples that are known at present, we discuss instructive cases that serve as paradigms for different modes of translational control.
引用
收藏
页码：827 / 835
页数：9
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