Presynaptic induction and expression of NMDA-dependent LTP

被引：21
|
作者：
Paré, D [1 ]
机构：
[1] Rutgers State Univ, Ctr Mol & Behav Neurosci, Newark, NJ 07102 USA
来源：
TRENDS IN NEUROSCIENCES | 2004年 / 27卷 / 08期
关键词：
D O I：
10.1016/j.tins.2004.05.004
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
It is almost axiomatic in neuroscience that postsynaptically induced NMDA-dependent long-term potentiation (LTP) is a cellular substrate of memory. As a result, memory impairments caused by experimental reductions of NMDA currents are often interpreted as evidence that this form of plasticity is involved in memory formation. However, a recent Nature study indicates that not all NMDA-dependent UP is induced postsynaptically.
引用
收藏
页码：440 / 441
页数：2
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