Microwave-Assisted Synthesis of 2-Aryl and 2,5-Diarylthiophene Derivatives via Suzuki-Miyaura Cross-Coupling Using Novel Palladium Complex as a Catalyst

被引：2

作者：

Khormi, Afaf Y. ^{[1
]}

Farghaly, Thoraya. A. ^{[2
,3
]}

Shaaban, Mohamed R. ^{[3
]}

机构：

[1] King Khalid Univ, Dept Chem, Fac Sci, Abha, Saudi Arabia

[2] Umm Al Qura Univ, Fac Sci Appl, Dept Chem, Makkah Almukaramah, Saudi Arabia

[3] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2022年 / 42卷 / 07期

关键词：

Catalysis; microwaves; palladium; pyrimidine; Suzuki-Miyaura cross-coupling; thiophenes; HECK;

D O I：

10.1080/10406638.2021.1874429

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel phosphine-free pyrimidine-based palladium(II) complex have been synthesized from easily accessible starting materials and its ability to be a catalyst for cross-coupling reactions namely, Suzuki-Miyaura (SMC) has been investigated. The structure of the new formamidinyl pyrimidine-based complex has been elucidated by using spectroscopic as well as physical characterization techniques. The novel palladium(II) complex showed its applicability as a catalyst for SMC of 2-bromothiophene and 2,5-dibromothiophene with arylboronic acids under conventional and microwaves irradiation conditions. The developed catalytic system exhibited reasonable catalytic activity to obtain 2-aryl and 2,5-diarylthiophene derivatives using mild reaction conditions.

引用

页码：3893 / 3907

页数：15

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