A Microreactor with Thousands of Subcompartments: Enzyme-Loaded Liposomes within Polymer Capsules

被引：168

作者：

Staedler, Brigitte ^{[1
]}

Chandrawati, Rona ^{[1
]}

Price, Andrew D. ^{[1
]}

Chong, Siow-Feng ^{[1
]}

Breheney, Kerry ^{[2
]}

Postma, Almar ^{[1
]}

Connal, Luke A. ^{[1
]}

Zelikin, Alexander N. ^{[1
]}

Caruso, Frank ^{[1
]}

机构：

[1] Univ Melbourne, Ctr Nanosci & Nanotechnol, Dept Chem & Biomol Engn, Parkville, Vic 3010, Australia

[2] CSIRO, Parkville, Vic 3052, Australia

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 24期

关键词：

capsules; cross-linking; enzymes; liposomes; polymers; MICROCAPSULES; SYSTEMS; FILMS;

D O I：

10.1002/anie.200900386

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fully loaded: Noncovalent anchoring of liposomes into polymer multilayered films with cholesterol-modified polymers allows the preparation of capsosomes - liposomecompartmentalized polymer capsules (see picture). A quantitative enzymatic reaction confirmed the presence of active cargo within the capsosomes and was used to determine the number of subcompartments within this novel biomedical carrier system. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4359 / 4362

页数：4

共 31 条

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