Advances in three-dimensional rapid prototyping of microfluidic devices for biological applications

被引：103

作者：

O'Neill, P. F. ^{[1
,2
]}

Ben Azouz, A. ^{[1
,2
,3
]}

Vazquez, M. ^{[1
,2
]}

Liu, J. ^{[1
]}

Marczak, S. ^{[4
]}

Slouka, Z. ^{[4
]}

Chang, H. C. ^{[4
]}

Diamond, D. ^{[3
]}

Brabazon, D. ^{[1
,2
]}

机构：

[1] Dublin City Univ, Sch Mech & Mfg Engn, Adv Proc Technol Res Ctr, Dublin 9, Ireland

[2] Dublin City Univ, Natl Ctr Sensor Res, Irish Separat Sci Cluster, Dublin 9, Ireland

[3] Dublin City Univ, Natl Ctr Sensor Res, Insight Ctr Data Analyt, Dublin 9, Ireland

[4] Univ Notre Dame, Ctr Microfluid & Med Diagnost, Notre Dame, IN 46556 USA

来源：

BIOMICROFLUIDICS | 2014年 / 8卷 / 05期

基金：

美国国家科学基金会; 爱尔兰科学基金会;

关键词：

ON-A-CHIP; FABRICATION; VERSATILE; CULTURE; SYSTEM; FUTURE; GLASS;

D O I：

10.1063/1.4898632

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The capability of 3D printing technologies for direct production of complex 3D structures in a single step has recently attracted an ever increasing interest within the field of microfluidics. Recently, ultrafast lasers have also allowed developing new methods for production of internal microfluidic channels within the bulk of glass and polymer materials by direct internal 3D laser writing. This review critically summarizes the latest advances in the production of microfluidic 3D structures by using 3D printing technologies and direct internal 3D laser writing fabrication methods. Current applications of these rapid prototyped microfluidic platforms in biology will be also discussed. These include imaging of cells and living organisms, electrochemical detection of viruses and neurotransmitters, and studies in drug transport and induced-release of adenosine triphosphate from erythrocytes. (C) 2014 AIP Publishing LLC.

引用

页数：11

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