Use of quetiapine in bipolar disorder: a case series with prospective evaluation

被引:21
作者
Suppes, T [1 ]
McElroy, SL [1 ]
Keck, PE [1 ]
Altshuler, L [1 ]
Frye, MA [1 ]
Grunze, H [1 ]
Leverich, GS [1 ]
Nolen, WA [1 ]
Chisholm, K [1 ]
Dennehy, EB [1 ]
Post, RM [1 ]
机构
[1] UT SW Med Ctr, Dept Psychiat, Dallas, TX 75390 USA
关键词
bipolar disorder; maintenance; outpatient; polypharmacy; quetiapine; treatment;
D O I
10.1097/00004850-200405000-00010
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Quetiapine, a new atypical antipsychotic, was added to ongoing treatment of bipolar I outpatients (n=15) for symptoms of illness (mood lability, irritability, psychosis and/or difficulty sleeping). All evaluations were prospectively obtained, with the majority of patients (n=9) showing much or very much improvement on the Clinical Global Impression for Bipolar Disorder (CGI-BP). Somatic complaints were limited. Mean (SD) duration before changes in medication regimens was 134 (100) days. Studies of the use of quetiapine in maintenance treatment of bipolar disorder are warranted. (C) 2004 Lippincott Williams Wilkins.
引用
收藏
页码:173 / 174
页数:2
相关论文
共 6 条
[1]   Extending indications for long-term pharmacotherapy: Opportunities and challenges [J].
Kane, JM .
AMERICAN JOURNAL OF PSYCHIATRY, 2002, 159 (01) :1-2
[2]   The Stanley Foundation Bipolar Treatment Outcome Network I. Longitudinal methodology [J].
Leverich, GS ;
Nolen, WA ;
Rush, AJ ;
McElroy, SL ;
Keck, PE ;
Denicoff, KD ;
Suppes, T ;
Altshuler, LL ;
Kupka, R ;
Kramlinger, KG ;
Post, RM .
JOURNAL OF AFFECTIVE DISORDERS, 2001, 67 (1-3) :33-44
[3]  
SACHS GS, 2002, 3 EUR STANL FDN C DI
[4]   Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study [J].
Tohen, M ;
Ketter, TA ;
Zarate, CA ;
Suppes, T ;
Frye, M ;
Altshuler, L ;
Zajecka, J ;
Schuh, LM ;
Risser, RC ;
Brown, E ;
Baker, RW .
AMERICAN JOURNAL OF PSYCHIATRY, 2003, 160 (07) :1263-1271
[5]  
TOHEN M, 2002, 3 EUR STANL FDN C BI
[6]   Quetiapine in the treatment of rapid cycling bipolar disorder [J].
Vieta, E ;
Parramon, G ;
Padrell, E ;
Nieto, E ;
Martinez-Arán, A ;
Corbella, B ;
Colom, F ;
Reinares, M ;
Goikolea, JM ;
Torrent, C .
BIPOLAR DISORDERS, 2002, 4 (05) :335-340