Quetiapine, a new atypical antipsychotic, was added to ongoing treatment of bipolar I outpatients (n=15) for symptoms of illness (mood lability, irritability, psychosis and/or difficulty sleeping). All evaluations were prospectively obtained, with the majority of patients (n=9) showing much or very much improvement on the Clinical Global Impression for Bipolar Disorder (CGI-BP). Somatic complaints were limited. Mean (SD) duration before changes in medication regimens was 134 (100) days. Studies of the use of quetiapine in maintenance treatment of bipolar disorder are warranted. (C) 2004 Lippincott Williams Wilkins.
机构:
Hillside Hosp, Long Isl Jewish Med Ctr, Dept Psychiat, Glen Oaks, NY 11004 USAHillside Hosp, Long Isl Jewish Med Ctr, Dept Psychiat, Glen Oaks, NY 11004 USA
机构:
Hillside Hosp, Long Isl Jewish Med Ctr, Dept Psychiat, Glen Oaks, NY 11004 USAHillside Hosp, Long Isl Jewish Med Ctr, Dept Psychiat, Glen Oaks, NY 11004 USA