The choice of whether to participate in a phase I clinical trial: increasing the awareness of patients with cancer. An exploratory study

被引:5
作者
Catania, C. [1 ]
Radice, D. [2 ]
Spitaleri, G. [1 ]
Adamoli, L. [1 ]
Noberasco, C. [1 ]
Delmonte, A. [1 ]
Vecchio, F. [1 ]
de Braud, F. [3 ]
Toffalorio, F. [1 ]
Goldhirsch, A. [4 ]
De Pas, T. [1 ]
机构
[1] European Inst Oncol, Clin Pharmacol & New Drugs Dev Div, Dept Med Oncol, I-20141 Milan, Italy
[2] European Inst Oncol, Epidemiol & Biostat Div, I-20141 Milan, Italy
[3] Fdn IRCCS Ist Nazl Tumori, Med Oncol Unit 1, Milan, Italy
[4] European Inst Oncol, Dept Med, I-20141 Milan, Italy
关键词
posttraumatic growth; posttraumatic stress; oncology; cancer survivor; PTSD; PATIENTS DECISION-MAKING; INFORMED-CONSENT; THERAPEUTIC MISCONCEPTION; COMMUNICATION; PHYSICIAN; REASONS; MODEL;
D O I
10.1002/pon.3424
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objective There are conflicting empirical data regarding the relationship between posttraumatic stress (PTS) and growth (PTG) observed in cancer survivors. Clarification of this association could inform evidence-based therapeutic recommendations to promote adjustment in survivors following a cancer diagnosis. Methods This cross-sectional study employed standardized measures to examine the association between PTS and PTG in a sample of long-term lymphoma survivors. In addition, associations between PTG and demographic, clinical and psychosocial variables were identified to inform clinical recommendations. Results Long-term survivors of non-Hodgkin lymphoma provided informed consent (n = 886; 74% response rate). Subjects averaged 10.2 years post-diagnosis and 62.9 years of age. No significant association was found between the PTS and PTG summary scores. Several demographic and clinical variables (e.g., female gender and greater social support) were independently associated with greater PTG. Conclusions Clinicians are advised to be attentive to psychosocial needs throughout the post-cancer diagnosis adjustment period by screening for PTS symptomatology and recognizing that survivors who report growth may also be highly distressed. Copyright (c) 2013 John Wiley & Sons, Ltd.
引用
收藏
页码:322 / 329
页数:8
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