TELOMERE DYSFUNCTION MEDIATES ANTI-TUMOR IMMUNITY IN SMALL CELL LUNG CANCER

被引：0
|
作者：
Zhu, Mingrui [1 ]
Eglenen-Polat, Buse [1 ]
Bender, Matthew [1 ]
Mender, Ilgen [1 ]
Siteni, Silvia [1 ]
Drapkin, Benjamin [1 ]
Shay, Jerry [1 ]
Akbay, Esra [1 ]
机构：
[1] UT SouthWestern Med Ctr, Dallas, TX USA
来源：
JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2022年 / 10卷
关键词：
D O I：
10.1136/jitc-2022-SITC2022.0906
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
906
引用
收藏
页码：A944 / A944
页数：1
相关论文
共 50 条
  • [1] A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer
    Buse Eglenen-Polat
    Ryan R. Kowash
    Hai-Cheng Huang
    Silvia Siteni
    Mingrui Zhu
    Kenian Chen
    Matthew E. Bender
    Ilgen Mender
    Victor Stastny
    Benjamin J. Drapkin
    Prithvi Raj
    John D. Minna
    Lin Xu
    Jerry W. Shay
    Esra A. Akbay
    Nature Communications, 15
  • [2] A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer
    Eglenen-Polat, Buse
    Kowash, Ryan R.
    Huang, Hai-Cheng
    Siteni, Silvia
    Zhu, Mingrui
    Chen, Kenian
    Bender, Matthew E.
    Mender, Ilgen
    Stastny, Victor
    Drapkin, Benjamin J.
    Raj, Prithvi
    Minna, John D.
    Xu, Lin
    Shay, Jerry W.
    Akbay, Esra A.
    NATURE COMMUNICATIONS, 2024, 15 (01)
  • [3] Anti-tumor immunity is a key determinant of small cell lung cancer survivorship
    Kosari, Farhad
    Muppa, Prasuna
    Terra, Simone
    Sharma, Anurag
    Mansfield, Aaron
    Aubry, Marie Christine
    Janaki, Nafiseh
    Nasir, Aqsa
    Peikert, Tobias
    CANCER RESEARCH, 2019, 79 (13)
  • [4] Role of CD38 in anti-tumor immunity of small cell lung cancer
    Taniguchi, Hirokazu
    Chavan, Shweta S.
    Chow, Andrew
    Chan, Joseph M.
    Mukae, Hiroshi
    Rudin, Charles M.
    Sen, Triparna
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [5] A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression
    Tang, Zhen
    Hu, Jing
    Li, Xu-Chang
    Wang, Wei
    Zhang, Han-Yue
    Guo, Yu-Yao
    Shuai, Xin
    Chu, Qian
    Xie, Conghua
    Lin, Dandan
    Zhong, Bo
    DEVELOPMENTAL CELL, 2025, 60 (03)
  • [6] B cell regulation in cancer and anti-tumor immunity
    Anushruti Sarvaria
    J Alejandro Madrigal
    Aurore Saudemont
    Cellular & Molecular Immunology, 2017, 14 : 662 - 674
  • [7] CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis
    Yan, Xi
    Niu, Yinghao
    Wang, Yaojie
    Wei, Sisi
    Han, Lina
    Guo, Zhongyu
    Zhao, Lianmei
    Gao, Feng
    OPEN MEDICINE, 2025, 20 (01):
  • [8] Bioavailability and anti-tumor activity of capsaicin in human small cell lung cancer
    Hurley, John D.
    Rollyson, William D.
    Stover, Cody A.
    Brown, Kathleen C.
    Perry, Haley E.
    Stevenson, Cathryn D.
    Crabtree, Clayton M.
    Dom, Aaron M.
    Lau, Jamie K.
    Witte, Theodore R.
    Hardman, W. E.
    Dasgupta, Piyali
    CANCER RESEARCH, 2015, 75
  • [9] CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer
    Zhang, Hua
    Christensen, Camilla L.
    Dries, Ruben
    Oser, Matthew G.
    Deng, Jiehui
    Diskin, Brian
    Li, Fei
    Pan, Yuanwang
    Zhang, Xuzhu
    Yin, Yandong
    Papadopoulos, Eleni
    Pyon, Val
    Thakurdin, Cassandra
    Kwiatkowski, Nicholas
    Jani, Kandarp
    Rabin, Alexandra R.
    Castro, Dayanne M.
    Chen, Ting
    Silver, Heather
    Huang, Qingyuan
    Bulatovic, Mirna
    Dowling, Catriona M.
    Sundberg, Belen
    Leggett, Alan
    Ranieri, Michela
    Han, Han
    Li, Shuai
    Yang, Annan
    Labbe, Kristen E.
    Almonte, Christina
    Sviderskiy, Vladislav O.
    Quinn, Max
    Donaghue, Jack
    Wang, Eric S.
    Zhang, Tinghu
    He, Zhixiang
    Velcheti, Vamsidhar
    Hammerman, Peter S.
    Freeman, Gordon J.
    Bonneau, Richard
    Kaelin, William G., Jr.
    Sutherland, Kate D.
    Kersbergen, Ariena
    Aguirre, Andrew J.
    Yuan, Guo-Cheng
    Rothenberg, Eli
    Miller, George
    Gray, Nathanael S.
    Wong, Kwok-Kin
    CANCER CELL, 2020, 37 (01) : 37 - +
  • [10] Obesity dependent benefits of metformin for improved anti-tumor immunity and outcomes in non-small cell lung cancer
    Barbi, Joseph
    Smith, Randall J.
    Zollo, Robert
    Sass, Stephanie N.
    Washington, Deschana
    Petrucci, Cara
    Srinivasan, Aravind
    Kannisto, Eric
    Patnaik, Santosh
    Yendamuri, Sai Sai
    CANCER RESEARCH, 2022, 82 (12)
12345