Pd(0)-Catalyzed Sequential C-N Bond Formation via Allylic and Aromatic C-H Amination of α-Methylstyrenes with Diaziridinone

被引：40
作者：
Ramirez, Thomas A. [1 ]
Wang, Qian [1 ]
Zhu, Yingguang [1 ]
Zheng, Huaiji [1 ]
Peng, Xingao [1 ]
Cornwall, Richard G. [1 ]
Shi, Yian [1 ]
机构：
[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 16期
基金：
美国国家卫生研究院;
关键词：
AEROBIC OXIDATIVE AMINATION; PD(II)-CATALYZED AMINATION; ASYMMETRIC-SYNTHESIS; TERMINAL ALKENES; PALLADIUM; DIAMINATION; ACTIVATION; REACTIVITY; AMIDATION; CARBON;
D O I：
10.1021/ol401935c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel Pd(0)-catalyzed sequential C-N bond formation process via allylic and aromatic C-H amination of alpha-methylstyrenes with di-tert-butyldiaziridinone, giving spirocyclic indolines in good yields, is described. Four C-N bonds and one Spiro quaternary carbon are generated in a single operation.
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收藏
页码：4210 / 4213
页数：4
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