In-vitro activity of teicoplanin and ceftriaxone in combination against pathogens involved in paediatric bone and joint infections

被引：0

作者：

Lhopital, S ^{[1
]}

Bonacorsi, S ^{[1
]}

Doit, C ^{[1
]}

Sandin, A ^{[1
]}

Bingen, E ^{[1
]}

机构：

[1] HOP ROBERT DEBRE,MICROBIOL LAB,F-75019 PARIS,FRANCE

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1996年 / 38卷 / 04期

关键词：

D O I：

10.1093/jac/38.4.713

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We investigated the combination of teicoplanin and ceftriaxone for its bactericidal activity against Staphylococcus aureus, Haemophilus influenzae type b and Streptococcus pneumoniae isolated from bone and joint infections in children. An increase in bactericidal activity was observed against isolates of S. aureus and H. influenzae when the antibiotics were tested at fractional MICs whereas indifference was observed at their MICs. Similar results were obtained at fractional MICs against S. pneumoniae, but the bactericidal activity fell by more than 1 x log 10 cfu/mL when the antibiotics were tested at or above their MICs.

引用

页码：713 / 718

页数：6

共 16 条

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