Chemiluminescence of copper nanoclusters and its application for trihexyphenidyl hydrochloride detection

被引：6

作者：

Chen, Xiaoxia ^{[1
]}

Zhang, Junmei ^{[1
]}

Li, Yue ^{[1
]}

Han, Suqin ^{[1
,2
]}

机构：

[1] Shanxi Normal Univ, Sch Chem & Mat Sci, Linfen 041000, Shanxi, Peoples R China

[2] Shanxi Normal Univ, Modern Coll Humanities & Sci, Dept Chem, Linfen, Shanxi, Peoples R China

来源：

LUMINESCENCE | 2018年 / 33卷 / 05期

关键词：

cerium(IV); chemiluminescence; copper nanoclusters; KMnO4; trihexyphenidyl hydrochloride; LIQUID-PHASE CHEMILUMINESCENCE; TEMPLATED CU NANOCLUSTERS; ELECTROGENERATED CHEMILUMINESCENCE; METAL NANOCLUSTERS; ENERGY-TRANSFER; QUANTUM DOTS; BENZHEXOL; ELECTROPHORESIS; PROBES; SENSOR;

D O I：

10.1002/bio.3496

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Chemiluminescence (CL) of copper nanoclusters (CuNCs) induced by cerium (IV) (Ce(IV)) or potassium permanganate (KMnO4) in acidic medium was observed. The potential application of CuNCs CL in analytical chemistry was also demonstrated using trihexyphenidyl hydrochloride (THP) as an example based on its enhancing CL intensity for the CuNCs-Ce(IV)/KMnO4 systems. The excited state of the CuNCs acted as a luminophore in the CuNCs-Ce(IV) system, while CuNCs played the role of reductant in the CuNCs-KMnO4 system. The increased CL intensity for Ce(IV)-CuNCs system was proportional to the THP concentrations in the range of 0.1 to 10.0M. The detection limit was 49.0nM and the relative standard deviation was 2.2% for 2.0M THP (n=11). The proposed method was applied to detect THP in pharmaceutical formulations and human plasma samples.

引用

页码：962 / 967

页数：6

共 35 条

[1] Determination of Trihexyphenidyl hydrochloride drug in tablets and urine using a potentiometric carbon paste electrode [J].

Abu Shawish, Hazem M. ;

Elhabiby, Mahmoud ;

Abu Aziz, Hadeel S. ;

Saadeh, Salman M. ;

Tbaza, Ahmad .

SENSORS AND ACTUATORS B-CHEMICAL, 2016, 235 :18-26

[2] Advances in the use of acidic potassium permanganate as a chemiluminescence reagent: A review [J].

Adcock, Jacqui L. ;

Barnett, Neil W. ;

Barrow, Colin J. ;

Francis, Paul S. .

ANALYTICA CHIMICA ACTA, 2014, 807 :9-28

[3] Application of chemiluminescence in the analysis of wastewaters - A review [J].

Antonio Ocana-Gonzalez, Juan ;

Ramos-Payan, Maria ;

Fernandez-Torres, Rut ;

Villar Navarro, Mercedes ;

Angel Bello-Lopez, Miguel .

TALANTA, 2014, 122 :214-222

[4] Copper nanocluster-enhanced luminol chemiluminescence for high-selectivity sensing of tryptophan and phenylalanine [J].

Borghei, Yasaman-Sadat ;

Hosseini, Morteza ;

Khoobi, Mehdi ;

Ganjali, Mohammad Reza .

LUMINESCENCE, 2017, 32 (06) :1045-1050

[5] Stereoselective determination of trihexyphenidyl in human serum by LC-ESI-MS [J].

Cápka, V ;

Xu, Y ;

Chen, YH .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1999, 21 (03) :507-517

[6] Synthesis of cysteine-functionalized water-soluble luminescent copper nanoclusters and their application to the determination of chromium(VI) [J].

Cui, Malin ;

Song, Ge ;

Wang, Chan ;

Song, Qijun .

MICROCHIMICA ACTA, 2015, 182 (7-8) :1371-1377

[7] Fluorescent silver nanoclusters [J].

Diez, Isabel ;

Ras, Robin H. A. .

NANOSCALE, 2011, 3 (05) :1963-1970

[8] Electrochemistry and electrogenerated chemiluminescence from silicon nanocrystal quantum dots [J].

Ding, ZF ;

Quinn, BM ;

Haram, SK ;

Pell, LE ;

Korgel, BA ;

Bard, AJ .

SCIENCE, 2002, 296 (5571) :1293-1297

[9] Recent advances in the analytical applications of copper nanoclusters [J].

Hu, Xue ;

Liu, Tingting ;

Zhuang, Yunxia ;

Wang, Wei ;

Li, Yinying ;

Fan, Wenhong ;

Huang, Yuming .

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2016, 77 :66-75

[10] Cu Nanoclusters with Aggregation Induced Emission Enhancement [J].

Jia, Xiaofang ;

Li, Jing ;

Wang, Erkang .

SMALL, 2013, 9 (22) :3873-3879

← 1 2 3 4 →