Clinical characteristics and pregnancy outcomes in parturients with pulmonary hypertension: experience with 39 consecutive cases from China

Purpose: The authors aimed to understand the clinical characteristics of pulmonary hypertension (PI I) with pregnancy and pregnancy outcomes in Chinese population. Materials and Methods: The authors retrospectively analyzed 39 parturients with Ph. The patients were divided into mild PH group (n = 20) and severe PH group (n = 19). They compared some clinical characteristics, as well as maternal and fetal outcomes between the mild and severe PH groups. Results: The diagnostic rate of PH before pregnancy was 7.7% and the overall maternal mortality was 15.4%. There was no significant difference in age, body mass index, average termination of gestation weeks, and New York I kart Association functional class pre-pregnancy between the mild and severe PI I groups. The mortality in the severe PH group (31.6%) was significantly higher than that in the mild PH group (0%) (p < 0. 05). In addition, the occurrence rate of post-partiun haemorrhage (PPH) and natality of low-birth weight neonates (LBWN) were significantly higher in the severe PH group (21.1%; 36.8%) than that in the mild PH group (0%; 10%) (p < 0. 05), respectively. Conclusion: The overall mortality of parturients with PH is high and severe PH increase the risk of death, occurrence rate of PPH, and natality of LBWN.