How common is human toxocariasis? Towards standardizing our knowledge

被引:214
作者
Smith, Huw [1 ]
Holland, Celia [2 ]
Taylor, Mervyn [2 ]
Magnaval, J-F. [3 ]
Schantz, Peter [4 ]
Maizels, Rick [5 ]
机构
[1] Stobhill Hosp, Scottish Parasite Diagnost Lab, Glasgow G21 3UW, Lanark, Scotland
[2] Trinity Coll Dublin, Dept Zool, Dublin 2, Ireland
[3] Fac Med Purpan, CNRS, FRE 2960, Serv Parasitol Med, F-31073 Toulouse 7, France
[4] Ctr Dis Control & Prevent, NCID, Div Parasit Dis, Atlanta, GA 30333 USA
[5] Univ Edinburgh, Ashworth Labs, Inst Immunol & Infect Res, Edinburgh EH9 3JT, Midlothian, Scotland
关键词
VISCERAL LARVA MIGRANS; C-TYPE LECTIN; ASCARIDOID NEMATODES; OCULAR TOXOCARIASIS; INFECTIVE LARVAE; CANIS; IMMUNODIAGNOSIS; ANTIGEN; DIAGNOSIS; CATI;
D O I
10.1016/j.pt.2009.01.006
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Our understanding of the global impact and cost of human toxocariasis is poor because there is insufficient clinical awareness and no clear repository for the efficacy of clinical, laboratory and treatment interventions. Uniform clinical and laboratory investigative approaches maximize disease diagnosis. International collaboration is required to develop web-based, professional educational support, surveillance questionnaires and standardized serodiagnostic criteria. Determining clinical benefits and treatment outcomes using less crossreactive antigens will enhance clinical and treatment interventions. Increased liaison will identify realistic occurrence and prevalence data and cost benefits of intervention. Web-based centres of excellence and repositories of current knowledge, which augment current veterinary and public health educational sites, should be supported. Expected outcomes should be capable of addressing the clinical and financial burdens of this treatable disease.
引用
收藏
页码:182 / 188
页数:7
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