Determination of bismuth in pharmaceutical products using liquid-liquid extraction in a flow injection system

被引：38

作者：

Alonso, A ^{[1
]}

Almendral, MJ ^{[1
]}

Báez, MD ^{[1
]}

Porras, MJ ^{[1
]}

Lávin, FL ^{[1
]}

de María, CG ^{[1
]}

机构：

[1] Univ Salamanca, Fac Chem, Dept Quim Analit Nutr & Bromatol, E-37008 Salamanca, Spain

来源：

ANALYTICA CHIMICA ACTA | 2000年 / 408卷 / 1-2期

关键词：

liquid-liquid extraction; flow injection; bismuth; ion-pair; pharmaceuticals;

D O I：

10.1016/S0003-2670(99)00768-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A flow injection procedure for the determination of bismuth in pharmaceutical products is described. The procedure is based on the formation of an ion-pair between tetraphenylarsonium and the tetraiodobismuthate(III) anion. This ion-pair is extracted with chloroform and the absorbance of the organic phase is measured at 363 or 505 nm. The detection Limit (3 x baseline s.d.) is 1.5 x 10(-6) M (35 ng). The proposed procedure has a relative standard deviation of 1.6% (3.0 x 10(-5) M, n = 12), a linear application range between 2.3 x 10(-6) and 1.5 x 10(-4) M and a sampling frequency of 40 h(-1). Under the proposed working conditions, only Pd(II), Pt(IV) and Au(III) interfere. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：129 / 133

页数：5

共 17 条

[1] BAISHYA NK, 1976, CURR SCI INDIA, V45, P94
[2] BAYAN KC, 1984, CURR SCI INDIA, V53, P312
[3] ANALYTICAL ASPECTS OF ORGANO-P AS SB S SE TE AND SN(4) (ONIUM) CATIONS
BOWD, AJ
THORBURN, D
FOGG, AG
[J]. TALANTA, 1969, 16 (06) : 719 - &
[4] FLOW-INJECTION EXTRACTION-SPECTROPHOTOMETRIC DETERMINATION OF PERCHLORATE WITH BRILLIANT GREEN
BURNS, DT
CHIMPALEE, N
HARRIOTT, M
[J]. ANALYTICA CHIMICA ACTA, 1989, 217 (01) : 177 - 181
[5] BURNS DT, 1987, ANAL CHIM ACTA, V197, P285
[6] SPECTROPHOTOMETRIC DETERMINATION OF BISMUTH AFTER EXTRACTION OF 1-NAPHTHYLMETHYLTRI-PHENYLPHOSPHONIUM TETRAIODOBISMUTHATE(III)
BURNS, DT
CHIMPALEE, D
[J]. ANALYTICA CHIMICA ACTA, 1988, 211 (1-2) : 305 - 309
[7] FLOW-INJECTION EXTRACTION-SPECTROPHOTOMETRIC DETERMINATION OF PERMANGANATE WITH THE ETHYLENE-BIS(TRIPHENYLPHOSPHONIUM) CATION
BURNS, DT
CHIMPALEE, N
HARRIOTT, M
MCKILLEN, GM
[J]. ANALYTICA CHIMICA ACTA, 1989, 217 (01) : 183 - 186
[8] The spectrophotometric determination of bismuth after extraction of protriptylinium tetraiodobismuthate(III)
Burns, DT
Dunford, MD
[J]. ANALYTICA CHIMICA ACTA, 1996, 334 (1-2) : 209 - 211
[9] USE OF BASIC DYES IN DETERMINATION OF ANIONS, PARTICULARLY AS A MEANS OF DETERMINING ANTIMONY, THALLIUM, AND GALLIUM
FOGG, AG
BURGESS, C
BURNS, DT
[J]. TALANTA, 1971, 18 (12) : 1175 - &
[10] Harriott M., 1989, ANAL P, V26, P315

← 1 2 →