Development and Pathology of Pulmonary Hypertension

被引:225
作者
Tuder, Rubin M. [1 ,2 ]
Abman, Steven H. [3 ]
Braun, Thomas [4 ]
Capron, Frederique [5 ]
Stevens, Troy [6 ]
Thistlethwaite, Patricia A. [7 ]
Haworth, Sheila G. [8 ]
机构
[1] Univ Colorado, Div Pulm Sci, Denver, CO 80202 USA
[2] Univ Colorado, Div Crit Care Med, Denver, CO 80202 USA
[3] Univ Colorado, Pediat Heart Lung Ctr, Denver, CO 80202 USA
[4] Max Planck Inst Heart Lung Res, Bad Nauheim, Germany
[5] Hop Pitie, Dept Pathol, F-75651 Paris, France
[6] Univ S Alabama, Coll Med, Ctr Lung Biol, Mobile, AL USA
[7] Univ Calif San Diego, Div Cardiothorac Surg, San Diego, CA 92103 USA
[8] UCL, Inst Child Hlth, Vasc Biol & Pharmacol Unit, London, England
基金
美国国家卫生研究院;
关键词
pulmonary hypertension; pulmonary circulation; angiogenesis; endothelial cell progenitor; pathology; ENDOTHELIAL PROGENITOR CELLS; BONE-MARROW; GROWTH-FACTOR; LUNG; PATHOGENESIS; VASCULATURE; ANGIOGENESIS; INHIBITION; DISEASE; INJURY;
D O I
10.1016/j.jacc.2009.04.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The Development and Pathology working group was charged with reviewing the present knowledge, gaps in understanding, and areas for further studies in a broad range of themes. These themes in pulmonary vascular biology and pathobiology involved: 1) pulmonary vascular development; 2) pulmonary vascular disease accompanying fetal development and perinatal life; 3) properties of pulmonary vascular endothelial cells; 4) role of bone marrow cells in pulmonary vascular disease; 5) insights into pulmonary thromboembolic disease; 6) role of pathology in the assessment of pulmonary vascular disease; and 7) considerations of tissue banking for research in pulmonary hypertension. These important goals provide a blueprint for future research that may significantly impact our present and future understanding of pulmonary hypertension. (J Am Coll Cardiol 2009;54:S3-9) (C) 2009 by the American College of Cardiology Foundation
引用
收藏
页码:S3 / S9
页数:7
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