Triterpene Biosynthesis in Plants

被引：576

作者：

Thimmappa, Ramesha ^{[1
]}

Geisler, Katrin ^{[1
]}

Louveau, Thomas ^{[1
]}

O'Maille, Paul ^{[1
,2
]}

Osbourn, Anne ^{[1
]}

机构：

[1] John Innes Ctr Plant Sci Res, Dept Metab Biol, Norwich NR4 7UH, Norfolk, England

[2] Inst Food Res, Food & Hlth Program, Norwich NR4 7UH, Norfolk, England

来源：

ANNUAL REVIEW OF PLANT BIOLOGY, VOL 65 | 2014年 / 65卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

oxidosqualene cyclases; metabolic gene clusters; specialized metabolites; sterols; synthetic biology; BETA-AMYRIN SYNTHASE; OXIDOSQUALENE-LANOSTEROL CYCLASE; CARBOXYPEPTIDASE-LIKE ACYLTRANSFERASES; ENCODING CYCLOARTENOL SYNTHASE; STEROID SAPONIN BIOSYNTHESIS; CELL-SUSPENSION CULTURES; METABOLIC GENE CLUSTERS; MOLECULAR-CLONING; FUNCTIONAL EXPRESSION; ARABIDOPSIS-THALIANA;

D O I：

10.1146/annurev-arplant-050312-120229

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The triterpenes are one of the most numerous and diverse groups of plant natural products. They are complex molecules that are, for the most part, beyond the reach of chemical synthesis. Simple triterpenes are components of surface waxes and specialized membranes and may potentially act as signaling molecules, whereas complex glycosylated triterpenes (saponins) provide protection against pathogens and pests. Simple and conjugated triterpenes have a wide range of applications in the food, health, and industrial biotechnology sectors. Here, we review recent developments in the field of triterpene biosynthesis, give an overview of the genes and enzymes that have been identified to date, and discuss strategies for discovering new triterpene biosynthetic pathways.

引用

页码：225 / 257

页数：33

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