Highly enantioselective reduction of symmetrical diacetylaromatics with baker's yeast

被引:15
|
作者
Uchiyama, M [1 ]
Katoh, N [1 ]
Mimura, R [1 ]
Yokota, N [1 ]
Shimogaichi, Y [1 ]
Shimazaki, M [1 ]
Ohta, A [1 ]
机构
[1] TOKYO UNIV PHARM & LIFE SCI,HACHIOJI,TOKYO 19203,JAPAN
关键词
D O I
10.1016/S0957-4166(97)00462-X
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Asymmetric reduction of symmetrical diacetylaromatics (1a, 1b, and 1d-g) with baker's yeast (Saccharomyces cerevisiae) provided the corresponding alcohols of high enantiomeric purity. By choosing appropriate reaction conditions, the products were preferentially the monoalcohols over the diols. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:3467 / 3474
页数:8
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